<scp>CD8</scp>⁺ T‐Lymphocyte–Driven Limbic Encephalitis Results in Temporal Lobe Epilepsy

Abstract

These data indicate that a CD8⁺ T-cell-initiated attack of distinct hippocampal neurons is sufficient to induce LE converting into TLE-HS. Intriguingly, the role of CD8⁺ T cells exceeds neurotoxic effects and points to their major pathogenic role in TLE following LE. ANN NEUROL 2021;89:666-685.