Life SciencesImmunologyNutritionAllergyBreastfeedingHypersensitivityAllergen ExposureAllergy PreventionEarly-life NutritionEnvironmental AllergensFood AllergensFood AllergyDietary Environmental ExposuresEarly Life HealthEarly-life StressEmollient UseImmunological ResponseInfant AllergyMaternal Diet During PregnancyTolerance-inducing Therapies
: Delivery by caesarean section, omission of breastfeeding, vitamin D insufficiency, and environmental exposures, such as cigarette smoke exposure, all increase the risk of an allergic predisposition. Dietary diversity during pregnancy, lactation, and in infancy is protective. Breastfeeding for at least 4 months reduces the risk of eczema. Recommendations for food-allergen exposure has shifted from delayed introduction to early introduction as a tolerance-inducing strategy. Supplements such as probiotics and vitamins during pregnancy and infancy have yet to produce conclusive results for allergy prevention. Emollient use in infancy has not been shown to be protective against eczema or food allergy.
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Randomized Trial of Peanut Consumption in Infants at Risk for Peanut Allergy
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Randomized Trial of Introduction of Allergenic Foods in Breast-Fed Infants
Michael R. Perkin, Kirsty Logan, Anna Tseng et al. · New England Journal of Medicine · 2016 · 877 citations · Full text
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