Concepedia

Tumor mutational burden on cytological samples: A pilot study

Francesco Pepe, Pasquale Pisapia, Valerio Gristina, Danilo Rocco, Mariacarolina Micheli, Pietro Micheli, Antonino Iaccarino, Rossella Tufano, Gianluca Gragnano, Gianluca Russo,

Cancer Cytopathology · 2020 · 46 citations · 29 references

DOIFull text

Open access

Abstract

In this pilot study, we demonstrated the technical feasibility of assessing TMB on CBs.

References

29

Cancer statistics, 2020

Rebecca L. Siegel, Kimberly D. Miller, Ahmedin Jemal · CA A Cancer Journal for Clinicians · 2020 · 21K citations · Full text

Pembrolizumab versus Chemotherapy for PD-L1–Positive Non–Small-Cell Lung Cancer

Martin Reck, Delvys Rodríguez‐Abreu, Andrew Robinson et al. · New England Journal of Medicine · 2016 · 9.8K citations · Full text

Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer

Naiyer A. Rizvi, Matthew D. Hellmann, Alexandra Snyder et al. · Science · 2015 · 7.8K citations · Full text

Pembrolizumab plus Chemotherapy in Metastatic Non–Small-Cell Lung Cancer

Leena Gandhi, Delvys Rodríguez‐Abreu, Shirish M. Gadgeel et al. · New England Journal of Medicine · 2018 · 6.4K citations · Full text

Tumor mutational load predicts survival after immunotherapy across multiple cancer types

Robert Samstein, Chung‐Han Lee, Alexander N. Shoushtari et al. · Nature Genetics · 2019 · 4.2K citations · Full text

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