<p>Beneficial Effects of Echinacoside on Diabetic Cardiomyopathy in Diabetic <em>Db/Db</em> Mice</p>

Abstract

ECH displays protective effects in DCM, including the inhibition of cardiac apoptosis and oxidative stress, and improved lipid metabolism in cardiomyocytes. ECH also inhibits cardiac apoptosis through its regulation of p53/p38MAPK signaling, and prevents lipid accumulation through suppression of the PPAR-α/M-CPT-1 signaling axis.