Upregulated Kynurenine Pathway Enzymes in Aortic Atherosclerotic Aneurysm: Macrophage Kynureninase Downregulates Inflammation - Concepedia

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Publication | Open Access

Upregulated Kynurenine Pathway Enzymes in Aortic Atherosclerotic Aneurysm: Macrophage Kynureninase Downregulates Inflammation

DOI Full Paper Access

18

Citations

28

References

2020

Year

Masanori Nishimura, Atsushi Yamashita, Yunosuke Matsuura, Junichi Okutsu, Aiko Fukahori, Tsuyoshi Hirata, Tomohiro Nishizawa, Hirohito Ishii, Kazunari Maekawa, Eriko Nakamura,

Journal of Atherosclerosis and Thrombosis

Abstract

Our study suggests the upregulation of the kynurenine pathway in macrophages in aortic atherosclerotic aneurysm. Kynureninase may negatively regulate inflammation via the kynurenine pathway itself in macrophages.

References

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