microRNA-155 Is Decreased During Atherosclerosis Regression and Is Increased in Urinary Extracellular Vesicles During Atherosclerosis Progression

Abstract

miR-155 suppresses anti-inflammatory signaling in macrophages, is decreased during regression of atherosclerosis <i>in vivo</i> and is increased in uEVs from patients with unstable CAD suggesting miR-155 has potential as a prognostic indicator and a therapeutic target.