The PKM2 activator TEPP‐46 suppresses kidney fibrosis via inhibition of the EMT program and aberrant glycolysis associated with suppression of HIF‐1α accumulation - Concepedia

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Publication | Open Access

The PKM2 activator TEPP‐46 suppresses kidney fibrosis via inhibition of the EMT program and aberrant glycolysis associated with suppression of HIF‐1α accumulation

DOI Full Paper Access

100

Citations

29

References

2020

Year

Haijie Liu, Yuta Takagaki, Asako Kumagai, Keizo Kanasaki, Daisuke Koya

Journal of Diabetes Investigation

Abstract

PKM2 activation could restore the tubular phenotype via suppression of the EMT program and aberrant glycolysis, providing an alternative target to mitigate fibrosis in diabetic kidneys.

References

	Year	Citations

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