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Publication | Open Access

TLR7/8 regulates type I and type III interferon signalling in rhinovirus 1b-induced allergic asthma

DOIFull Paper Access

36

Citations

25

References

2020

Year

Jasmin Krug, Alexander Kiefer, Julia Koelle, Tytti Vuorinen, Paraskevi Xepapadaki, Barbara Stanić, Mircea T. Chiriac, Mübeccel Akdiş, Theodor Zimmermann, Nikolaos G. Papadopoulos,
European Respiratory Journal

Abstract

In PBMCs from pre-school age children, IFN-αR mRNA was reduced and IFN-λR1 mRNA was induced upon treatment with the TLR7/8 agonist R848, thus suggesting new avenues for induction of antiviral immune responses in paediatric asthma.

References

YearCitations

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