STAT3/IL-6 dependent induction of inflammatory response in osteoblast and osteoclast formation in nanoscale wear particle-induced aseptic prosthesis loosening - Concepedia

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STAT3/IL-6 dependent induction of inflammatory response in osteoblast and osteoclast formation in nanoscale wear particle-induced aseptic prosthesis loosening

28

Citations

17

References

2020

Year

Zhantao Deng, Ruiying Zhang, Mengyuan Li, Shuai Wang, Guangtao Fu, Jiewen Jin, Zhenheng Wang, Yuanchen Ma, Qiujian Zheng

Biomaterials Science

Abstract

STAT3 mediated inflammation-related signalling and osteoclast activation in nanoscale wear particle-induced aseptic loosening. Inhibition of STAT3 by tofacitinib may be a potential treatment for aseptic loosening.

References

	Year	Citations

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