Concepedia

A strategic Ser/Cys exchange in the catalytic triad unlocks an acyltransferase-mediated synthesis of thioesters and tertiary amides

Martina Letizia Contente, David Roura Padrosa, Francesco Molinari, Francesca Paradisi

Nature Catalysis · 2020 · 48 citations · 31 references

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References

31

<i>MMPBSA.py</i>: An Efficient Program for End-State Free Energy Calculations

Bill R. Miller, T. Dwight McGee, Jason Swails et al. · Journal of Chemical Theory and Computation · 2012 · 4.5K citations

, , +17

Mapping optogenetically-driven single-vessel fMRI with concurrent neuronal calcium recordings in the rat hippocampus

Xuming Chen, Filip Sobczak, Yi Chen et al. · Nature Communications · 2019 · 249 citations · Full text

, , +17

The conversion of serine at the active site of subtilisin to cysteine: a "chemical mutation".

Kenneth Neet, Daniel E. Koshland · Proceedings of the National Academy of Sciences · 1966 · 193 citations

, , +10

A New Enzyme Containing a Synthetically Formed Active Site. Thiol-Subtilisin <sup>1</sup>

László Polgár, Myron L. Bender · Journal of the American Chemical Society · 1966 · 178 citations

, , +8

Enzyme‐Catalysed Synthesis of Secondary and Tertiary Amides

Mark Petchey, Gideon Grogan · Advanced Synthesis & Catalysis · 2019 · 118 citations

, , +14