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The nutrient sensing pathways FoxO1/3 and mTOR in the heart are coordinately regulated by central leptin through PPARβ/δ. Implications in cardiac remodeling

Energy HomeostasisDevelopmental BiologySignal TransductionMolecular PhysiologyNutrient SignallingPhysiologyCentral LeptinMetabolic RegulationCardiac RemodelingEndocrinologyMetabolismMetabolic SignalingMedicineCell SignalingMolecular Signaling