Selective packaged circular RNAs in milk extracellular vesicles during <i>Staphylococcus aureus</i> infection may have potential against bacterial infection

Abstract

infection. Moreover, we demonstrated that circRNAs were selectively packaged into EVs. Finally, bioinformatic analyses predicted the involvement of differentially expressed circRNAs in immune functions. In summary, our findings offer an insight into the packaging mechanism of EV circRNAs and underscore the potential by which host used the EV circRNAs in response to pathogenic bacterial infections.