Concepedia

Publication | Open Access

Distinct Genomic Profiles are Associated With Conversion to Resection and Survival in Patients With Initially Unresectable Colorectal Liver Metastases Treated With Systemic and Hepatic Artery Chemotherapy

DOIFull Paper Access

23

Citations

33

References

2020

Year

Jashodeep Datta, Raja R. Narayan, Debra A. Goldman, Walid K. Chatila, Mithat Gönen, James S. Strong, Vinod P. Balachandran, Jeffrey A. Drebin, T. Peter Kingham, William R. Jarnagin,
Annals of Surgery

Abstract

Distinct genomic profiles are associated with CTR and survival in patients with IU-CRLM treated with HAI/systemic chemotherapy. Presence of SOX9, BRAF , and co-altered RAS/RAF- TP53 mutations are promising biomarkers that, when validated in larger datasets, may impact treatment of IU-CRLM patients.

References

YearCitations

Page 1