PubMed · 1990 · 30 citations · 29 references
MedicineSurgeryGastroenterologyGeneral SurgerySurgical OncologyAbdominal SurgeryPancreatic CancerPancreatic DiseasesPancreatic DisordersPancreatic PathologyPancreatic SurgeryBiliary AnastomosisDuctal AnastomosisIntestinal AnastomosisPancreatic Cancer ResectionPancreatic Surgery Complications ManagementPostoperative Pancreatic ComplicationsSurgical Pancreatic Intervention
Although the mortality following pancreaticoduodenectomy has fallen and is now below 5%, overall 14% of patients develop a leak at the pancreatic anastomosis. This complication carries a 24% mortality rate when pancreaticojejunostomy is the method of reconstruction. In order to reduce the incidence of this complication, pancreaticogastrostomy can be performed following pancreaticoduodenectomy. A total of 41 patients underwent this operation between 1968 and 1989. The indications for operations were carcinoma of the head of the pancreas (n = 19), carcinoma of the ampulla (n = 12), carcinoma of the lower end of the common bile duct (n = 6), chronic pancreatitis (n = 3) and one patient with a nonfunctioning islet cell tumour. One patient developed a pancreatic fistula which closed spontaneously in 5 days. This patient is alive and well 36 months after operation. Pancreaticogastrostomy with pancreatic duct to gastric mucosa anastomosis is recommended as a safe and straight-forward method of reconstruction following pancreaticoduodenectomy.
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Decreased morbidity and mortality after pancreatoduodenectomy
Pierce A. Grace, Henry A. Pitt, Ronald K. Tompkins et al. · The American Journal of Surgery · 1986 · 438 citations
The Complications of Pancreatectomy
M. Trede, B. Chir, G. Schwall · Annals of Surgery · 1988 · 423 citations
Medicine, Surgery, General Surgery +16
John R. Brooks, J. M. Culebras · The American Journal of Surgery · 1976 · 186 citations
Surgical Experience with Pancreatic and Periampullary Cancer
Frederic P. Herter, Avram M. Cooperman, Thomas N. Ahlborn et al. · Annals of Surgery · 1982 · 181 citations
J. Lerut, Pierre Gianello, Jean‐Bernard Otte et al. · Annals of Surgery · 1984 · 176 citations · Full text
Medicine, Surgery, Gastroenterology +13