Abnormal Connectivity and Brain Structure in Patients With Visual Snow

Abstract

This study found VS to be associated with both functional and structural changes in the early and higher visual cortex, as well as the temporal cortex. These brain regions are involved in visual processing, memory, spatial attention, and cognitive control. We conclude that VS is not just confined to the visual system and that both functional and structural changes arise in VS patients, be it as an epiphenomenon or a direct contributor to the pathomechanism of VS. These <i>in vivo</i> neuroimaging biomarkers may hold potential as objective outcome measures of this so far purely subjective condition.