Analysis of skin tissues spatial fluorescence distribution by the Monte Carlo
\nsimulation

Abstract

A novel Monte Carlo technique of simulation of spatial fluorescence distribution
\nwithin the human skin is presented. The computational model of skin takes into
\naccount the spatial distribution of fluorophores, which would arise due to the
\nstructure of collagen fibres, compared to the epidermis and stratum corneum
\nwhere the distribution of fluorophores is assumed to be homogeneous. The results
\nof simulation suggest that distribution of auto-fluorescence is significantly
\nsuppressed in the near-infrared spectral region, whereas the spatial
\ndistribution of fluorescence sources within a sensor layer embedded in the
\nepidermis is localized at an ‘effective’ de