γ-Hydroxybutyric acid and 5-fluorouracil, metabolites of UFT, inhibit the angiogenesis induced by vascular endothelial growth factor

Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis

Dianna H. Ausprunk, Judah Folkman · Microvascular Research · 1977 · 1.3K citations

Medicine, Cell Biology, Oncology +16

Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer.

Yutaka Takahashi, Yasuhiko Kitadai, Corazon D. Bucana et al. · PubMed · 1995 · 1.3K citations

Medicine, Oncology, Pathology +17

Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

B Millauer, Laura K. Shawver, Karl H. Plate et al. · Nature · 1994 · 1.2K citations

Medicine, Cancer Biology, Oncology +12

SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types.

T. Annie T. Fong, Laura K. Shawver, Li Sun et al. · PubMed · 1999 · 1K citations

Medicine, Oncology, Pharmacology +16

Prognostic value of vascular endothelial growth factor expression in gastric carcinoma

Kiyoshi Maeda, Yong Suk Chung, Yoshinari Ogawa et al. · Cancer · 1996 · 633 citations

Medicine, Oncology, Pathology +17