Parmosidone K, a new <i>meta</i>-depsidone from the lichen <i>Parmotrema tsavoense</i>

Abstract

Further phytochemical investigation on <i>P. tsavoense</i> led to one new <i>meta</i>-depsidone, parmosidone K together with one known compound, barbatic acid. Their structures were determined by 1D and 2D NMR analysis, high resolution mass spectroscopy, and comparison their NMR data with those reported in literatures. Parmosidone K was evaluated for α-glucosidase inhibition and revealed the powerful activity with IC₅₀ value of 3.12 µM.