ENDURACIDIN, A NEW ANTIBIOTIC. II

Abstract

Enduracidin is a basic compound with ultraviolet absorption maxima at 230 and 263mμ in 90% methanol and is a colorless crystalline powder de composing at 225-240°C. It is positive to DRAGENDORFF, ninhydrin, BIURET and BARTON'S1) reagents but negative to Molisch reagent. Hydrolysis of en duracidin with 6n HC1 yields, aspartic acid, threonine (and/or allo-threonine), serine, glycine, alanine, ornithine, citrulline, α-amino-4-hydroxyphenylacetic acid, α-amino-3, 5-dichloro-4-hydroxyphenylacetic acid and two unidentified basic amino acids.