<i>IDH</i>-wildtype lower-grade diffuse gliomas: the importance of histological grade and molecular assessment for prognostic stratification

Abstract

Our findings highlight the importance of histological grading and molecular profiling for the prognostic stratification of IDHwt gliomas and suggest some caution when assimilating IDHwt grade II gliomas to molecular glioblastomas, especially those with isolated TERT promoter mutation.