Genetically engineered macrophages persist in solid tumors and locally deliver therapeutic proteins to activate immune responses - Concepedia

Concepedia

Publication | Open Access

Genetically engineered macrophages persist in solid tumors and locally deliver therapeutic proteins to activate immune responses

DOI Full Paper Access

80

Citations

35

References

2020

Year

Katherine J. Brempelis, Courtney M Cowan, Shannon Kreuser, Kevin P. Labadie, Brooke M Prieskorn, Nicole A. P. Lieberman, Chibawanye Ene, Kara White Moyes, Harrison Chinn, Kole DeGolier,

Journal for ImmunoTherapy of Cancer

Abstract

Our data demonstrate that GEMs can precisely deliver titratable doses of therapeutic proteins to the TME to improve safety, tissue penetrance, targeted delivery and pharmacokinetics.

References

	Year	Citations

Page 1