TPP1 Enhances the Therapeutic Effects of Transplanted Aged Mesenchymal Stem Cells in Infarcted Hearts via the MRE11/AKT Pathway - Concepedia

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TPP1 Enhances the Therapeutic Effects of Transplanted Aged Mesenchymal Stem Cells in Infarcted Hearts via the MRE11/AKT Pathway

DOI Full Paper Access

12

Citations

20

References

2020

Year

Kaixiang Yu, Zhiru Zeng, Si Cheng, Wangxing Hu, Chenyang Gao, Feng Liu, Jinyong Chen, Yi Qian, Dilin Xu, Jing Zhao,

Frontiers in Cell and Developmental Biology

Abstract

Our results reveal that TPP1 can enhance DNA repair through the AKT/MRE11 pathway, thereby improving the therapeutic effects of aged MSC transplantation and offering significant potential for the clinical application of autologous transplantation in aged patients.

References

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