Theranostics · 2020 · 85 citations · 3 references
MedicineMolecular BiologyOncologyMolecular OncologyTranscriptional RegulationTumor ProgressionCancer Cell SignalingEpigenetic Regulation In CancerGastric CancerOncogenic ProliferationOncogenic Signaling PathwaysSignal Transduction In CancerCancer Signaling PathwaysEpigenetics Of Gastric CancerMolecular Mechanisms Of CarcinogenesisPhosphorylation-dependent RegulationPleomorphic Adenoma CarcinomaProtein DeubiquitinationZinc Finger ProteinsZinc Finger Transcription Factors
In general, PLAGL2 promotes the proliferation and migration of GC cells through USP37-mediated deubiquitination of Snail1 protein. This work provided potential therapeutic targets for GC treatment.
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Anna-Karin Åström, Marianne L. Voz, Koen Kas et al. · PubMed · 1999 · 157 citations
Bo Liu, Chong Lu, Yongxi Song et al. · PubMed · 2014 · 24 citations
USP37 is a SNAI1 deubiquitinase.
Zhenna Xiao, Liang Chang, Jongchan Kim et al. · PubMed · 2019 · 16 citations · Full text