Concepedia

A Network Pharmacology to Explore the Mechanism of <i>Astragalus</i> Membranaceus in the Treatment of Diabetic Retinopathy

Qi Jin, Xiaofeng Hao, Like Xie, Jing Xu, Sun Mei, Hang Yuan, Shihui Wang, Gai-Ping Wu, Miao Meng-lu

Evidence-based Complementary and Alternative Medicine · 2020 · 20 citations · 32 references

DOIFull text

Open access

Abstract

AM treats DR through multiple compounds, multiple targets, and multiple pathways. AM may play a role in the treatment of DR by targeting VEGFA, AKT1, and IL-6 and participating in oxidative stress, angiogenesis, and inflammation.

References

32

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

Yingyao Zhou, Bin Zhou, Lars Pache et al. · Nature Communications · 2019 · 14.9K citations · Full text

Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

Theo Vos, Amanuel Alemu Abajobir, Kalkidan Hassen Abate et al. · The Lancet · 2017 · 13.3K citations · Full text

The GeneCards Suite: From Gene Data Mining to Disease Genome Sequence Analyses

Gil Stelzer, Naomi Rosen, Inbar Plaschkes et al. · Current Protocols in Bioinformatics · 2016 · 5.1K citations

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TCMSP: a database of systems pharmacology for drug discovery from herbal medicines

Jinlong Ru, Peng Li, Jinan Wang et al. · Journal of Cheminformatics · 2014 · 4.8K citations · Full text

SwissTargetPrediction: updated data and new features for efficient prediction of protein targets of small molecules

Antoine Daina, Olivier Michielin, Vincent Zoete · Nucleic Acids Research · 2019 · 3.8K citations · Full text