Concepedia

CD34 expression does not correlate with immunophenotypic stem cell or progenitor content in human cord blood products

Sruthi Mantri, Andreas Reinisch, Beruh Dejene, Deirdre J. Lyell, David DiGiusto, Rajni Agarwal‐Hashmi, Ravindra Majeti, Kenneth I. Weinberg, Matthew H. Porteus

Blood Advances · 2020 · 12 citations · 19 references

DOIFull text

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Concepts

Abstract

Key Points The CD34+ compartment of human cord blood contains a range of HSPC immunophenotypes, among which the Lin−CD34+CD38+CD127+ CLP is rare. There is no correlation between the frequencies of CD34+ cells and immunophenotypic HSC in umbilical cord blood products.

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