HMGB1 released from GSDME-mediated pyroptotic epithelial cells participates in the tumorigenesis of colitis-associated colorectal cancer through the ERK1/2 pathway

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Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

Jianjin Shi, Yue Zhao, Kun Wang et al. · Nature · 2015 · 6.2K citations

Inflammation, Signal Transduction, Signaling Pathway +12

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Rebecca L. Siegel, Kimberly D. Miller, Ann Goding Sauer et al. · CA A Cancer Journal for Clinicians · 2020 · 5K citations · Full text

Surgical Oncology, Epidemiology Of Cancer, Gastroenterology +21

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

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Medicine, Apoptosis, Pyroptosis +9

Chemically induced mouse models of acute and chronic intestinal inflammation

Stefan Wirtz, Vanessa Popp, Markus Kindermann et al. · Nature Protocols · 2017 · 1.4K citations

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