Prevalence of CBAVD in azoospermic men carrying pathogenic <i>CFTR</i> mutations ‐ Evaluated in a cohort of 639 non‐vasectomized azoospermic men

Abstract

CBAVD was found in ~ 44% of men with ΔF508/R117H mutations. The data may support that CFTR mutations might affect male fertility through other mechanisms than obstruction of the genital tract. For a practical, clinical purpose analysis for only ΔF508, R117H and IVS8-5T seems sufficient until further research shows anything else.