Atipamezole, a specific α<sub>2A</sub> antagonist, suppresses spike‐and‐wave discharges and alters Ca<sup>2⁺</sup>/calmodulin‐dependent protein kinase II in the thalamus of genetic absence epilepsy rats - Concepedia

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Atipamezole, a specific α<sub>2A</sub> antagonist, suppresses spike‐and‐wave discharges and alters Ca<sup>2⁺</sup>/calmodulin‐dependent protein kinase II in the thalamus of genetic absence epilepsy rats

14

Citations

40

References

2020

Year

Melis Yavuz, Banu Aydın, Nihan Çarçak, Özlem Akman, Hasan Raci Yananlı, Filiz Onat

Abstract

This study emphasizes the α<sub>2</sub> AR-related modulation of absence epilepsy and particularly the significance of α<sub>2</sub> AR antagonism in suppressing SWDs. Atipamezole's SWD-suppressive actions may be through CaMKII-mediated second messenger systems in the thalamus.

References

	Year	Citations

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