Concepedia

What can reaction databases teach us about Buchwald–Hartwig cross-couplings?

Martin Fitzner, Georg Wuitschik, Raffael Koller, Jean‐Michel Adam, Torsten Schindler, Jean‐Louis Reymond

Chemical Science · 2020 · 77 citations · 24 references

DOIFull text

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Concepts

Abstract

An analysis of the entire literature on Pd-catalyzed C–N couplings enables data-driven insight and provides recommendations for reaction conditions.

References

24

Zipf Distribution of U.S. Firm Sizes

Robert L. Axtell · Science · 2001 · 1.8K citations

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Why is Tanimoto index an appropriate choice for fingerprint-based similarity calculations?

Dávid Bajusz, Anita Rácz, Károly Héberger · Journal of Cheminformatics · 2015 · 1.6K citations · Full text

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Predicting reaction performance in C–N cross-coupling using machine learning

Derek T. Ahneman, Jesús G. Estrada, Shishi Lin et al. · Science · 2018 · 1.1K citations

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A Simple Catalytic Method for the Conversion of Aryl Bromides to Arylamines

Anil S. Guram, Roger A. Rennels, Stephen L. Buchwald · Angewandte Chemie International Edition in English · 1995 · 1K citations

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Palladium-catalyzed synthesis of arylamines from aryl halides. Mechanistic studies lead to coupling in the absence of tin reagents

Janis Louie, John F. Hartwig · Tetrahedron Letters · 1995 · 887 citations · Full text

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