Sustained Response After Remdesivir and Convalescent Plasma Therapy in a B-Cell–Depleted Patient With Protracted Coronavirus Disease 2019 (COVID-19)

Jakob Malsy, Luzia Veletzky, Janna Heide, Annette Hennigs, Ines Gil-Ibanez, Alexander Stein, Marc Lütgehetmann, Ulrich Rosien, Dorothea Jasper, Sven Peine,

Clinical Infectious Diseases · 2020 · 55 citations · 7 references

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Abstract

We provide detailed clinical, virological, and immunological data of a B-cell-depleted patient treated with obinutuzumab for follicular lymphoma with protracted coronavirus disease 2019 (COVID-19) and viremia. A sustained response was achieved after 2 courses of remdesivir and subsequent convalescent plasma therapy. Immunocompromised patients might require combined and prolonged antiviral treatment regimens.

References

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