Natriuretic Peptide B Type Test

Abstract

B-type natriuretic peptide (BNP) is a hormone secreted from cardiac ventricular myocytes in response to myocardial stretch and stress. Its release activates a cascade of pathways resulting in an overall protective effect on the myocardium, particularly natriuresis and vasodilation. Serum BNP levels become increased in patients with congestive heart failure (CHF) and are clinically useful in diagnosing and excluding CHF exacerbation. Increased levels may also predict the prognosis and adverse outcomes of patients with cardiac disease.