Hesperetin, a SIRT1 activator, inhibits hepatic inflammation via AMPK/CREB pathway

NF-κB signaling in inflammation

Ting Liu, Lingyun Zhang, Donghyun Joo et al. · Signal Transduction and Targeted Therapy · 2017 · 8.1K citations · Full text

Life Sciences, Immunology, Pathology +17

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

Konrad T. Howitz, Kevin J. Bitterman, Haim Cohen et al. · Nature · 2003 · 3.8K citations

Education, Genetics, Molecular Biology +12

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

Carles Cantó, Zachary Gerhart‐Hines, Jérôme N. Feige et al. · Nature · 2009 · 3.2K citations · Full text

Life Sciences, Biochemistry, Cell Biology +15

Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase

Fan Yeung, Jamie E. Hoberg, C S Ramsey et al. · The EMBO Journal · 2004 · 2.7K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +16

SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function

Nathan L. Price, Ana P. Gomes, Alvin J. Y. Ling et al. · Cell Metabolism · 2012 · 1.6K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15