Inhaled corticosteroids downregulate the SARS-CoV-2 receptor ACE2 in COPD through suppression of type I interferon - Concepedia

Concepedia

Publication | Open Access

Inhaled corticosteroids downregulate the SARS-CoV-2 receptor ACE2 in COPD through suppression of type I interferon

DOI Full Paper Access

152

Citations

37

References

2020

Year

Lydia Finney, Nicholas Glanville, Hugo Farne, Julia Aniscenko, Peter Fenwick, Samuel V. Kemp, Maria-Belen Trujillo-Torralbo, Su-Ling Loo, Maria Adelaide Calderazzo, Jadwiga A. Wedzicha,

Journal of Allergy and Clinical Immunology

Abstract

ICS therapies in COPD reduce expression of the SARS-CoV-2 entry receptor ACE2. This effect may thus contribute to altered susceptibility to COVID-19 in patients with COPD.

References

	Year	Citations

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