Concepedia

Pyruvate dehydrogenase kinase/lactate axis: a therapeutic target for neovascular age-related macular degeneration identified by metabolomics

Vincent Lambert, Sylvain Hansen, Matthieu Schoumacher, Julie Lecomte, Justine Leenders, Pascale Hubert, Michaël Herfs, Silvia Blacher, Oriane Carnet, Cassandre Yip,

Journal of Molecular Medicine · 2020 · 21 citations · 30 references

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30

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid

Oscar R. Colegio, Ngoc-Quynh Chu, Alison L. Szabo et al. · Nature · 2014 · 2.9K citations

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Role of PFKFB3-Driven Glycolysis in Vessel Sprouting

Katrien De Bock, Sandra Schoors, Anna Kuchnio et al. · Cell · 2013 · 1.6K citations · Full text

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Anti-inflammatory M2, but not pro-inflammatory M1 macrophages promote angiogenesis in vivo

Nadine Jetten, Sanne Verbruggen, Marion J. Gijbels et al. · Angiogenesis · 2013 · 844 citations

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Metabolomics enables precision medicine: “A White Paper, Community Perspective”

Richard D. Beger, Warwick B. Dunn, Michael A. Schmidt et al. · Metabolomics · 2016 · 615 citations · Full text

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Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer

David M. Brizel, Thies Schroeder, Richard L. Scher et al. · International Journal of Radiation Oncology*Biology*Physics · 2001 · 578 citations

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