Surface modified small intestinal submucosa membrane manipulates sequential immunomodulation coupled with enhanced angio- and osteogenesis towards ameliorative guided bone regeneration

Sequential delivery of immunomodulatory cytokines to facilitate the M1-to-M2 transition of macrophages and enhance vascularization of bone scaffolds

Kara L. Spiller, Sina Nassiri, Claire E. Witherel et al. · Biomaterials · 2014 · 773 citations · Full text

Engineering, Biomedical Engineering, Immunology +17

Macrophage Phenotype as a Determinant of Biologic Scaffold Remodeling

Stephen F. Badylak, Jolene E. Valentin, Anjani Ravindra et al. · Tissue Engineering Part A · 2008 · 727 citations

Engineering, Bioengineering, Biomedical Engineering +17

Osteoimmunomodulation for the development of advanced bone biomaterials

Zetao Chen, Travis J. Klein, Rachael Z. Murray et al. · Materials Today · 2015 · 708 citations · Full text

Engineering, Bioengineering, Biomedical Engineering +17

Periosteal matrix-derived hydrogel promotes bone repair through an early immune regulation coupled with enhanced angio- and osteogenesis

Pengcheng Qiu, Mobai Li, Kai Chen et al. · Biomaterials · 2019 · 343 citations

Engineering, Bioengineering, Orthopaedic Surgery +14

Promoting in vivo early angiogenesis with sub-micrometer strontium-contained bioactive microspheres through modulating macrophage phenotypes

Fujian Zhao, Bo Lei, Xian Li et al. · Biomaterials · 2018 · 281 citations

Engineering, Bioengineering, Biomedical Engineering +16