Advanced Functional Materials · 2020 · 10 citations · 0 references
Natural SciencesBioengineeringBiomedical EngineeringBiomaterialsDrug DeliveryTransdermal Drug DeliveryDrug Delivery BiomaterialsGelsHydrogelsNanocarriers For TherapeuticsNanomaterials For Drug DeliveryNanoparticle DesignAdhesive HydrogelsAdhesivenessHydrogel PatchesMesoporous Silica NanomaterialsMesoporous Silica NanoparticlesSilica-based NanoparticlesSkin AdhesionTransdermal Delivery Systems
In article number 2004407, Jaeyun Kim and co-workers describe a hydrogel patch with enhanced strength and high adhesiveness to skin tissue. The incorporation of mesoporous silica nanoparticles within the polydopamine-based hydrogel and between the hydrogel-tissue interface leads to significant enhancements of adhesiveness of the hydrogel to skin. The rapid adhesion and sustained drug delivery through the skin could allow for a hydrogel patch for transdermal drug delivery.