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Intratumoral Injection of <i>Clostridium novyi</i> -NT Spores in Patients with Treatment-refractory Advanced Solid Tumors

DOIFull Paper Access

139

Citations

20

References

2020

Year

Filip Jankú, Halle Huihong Zhang, Abdulmohammad Pezeshki, Sanjay Goel, Ravi Murthy, Andrea Wang‐Gillam, Dale R. Shepard, Thorunn Helgason, Tyler Masters, David S. Hong,
Clinical Cancer Research

Abstract

Single intratumoral injection of <i>C. novyi-</i>NT is feasible. Toxicities can be significant but manageable. Signals of antitumor activity and the host immune response support additional studies of <i>C. novyi-</i>NT in humans.

References

YearCitations

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