Small organic molecule-based nanoparticles with red/near-infrared aggregation-induced emission for bioimaging and PDT/PTT synergistic therapy

Abstract

An organic small molecule <bold>T-BDP</bold> with D–A–D structure was designed and synthesized and could self-assemble into nanoparticles with significant AIE performance. Under 635 nm laser irradiation, <bold>T-BDP NPs</bold> ablate cancer cells through photodynamic/photothermal synergistic effects.