Small organic molecule-based nanoparticles with red/near-infrared aggregation-induced emission for bioimaging and PDT/PTT synergistic therapy

Mengqian Yang, Jingran Deng, Huifang Su, Shuang‐Xi Gu, Jie Zhang, Aiguo Zhong, Fengshou Wu

Materials Chemistry Frontiers · 2020 · 96 citations · 48 references

Concepts

Abstract

An organic small molecule <bold>T-BDP</bold> with D–A–D structure was designed and synthesized and could self-assemble into nanoparticles with significant AIE performance. Under 635 nm laser irradiation, <bold>T-BDP NPs</bold> ablate cancer cells through photodynamic/photothermal synergistic effects.

References

48