Regioselective Synthesis of Halotriazoles and their Utility in Metal Catalyzed Coupling Reactions

Abstract

Synthesis of halotriazoles has been studied in the past few decades. Today, coupling reactions such as Heck, Suzuki, Sonogashira, and Stille are important tools in organic synthesis for the construction of C–C bonds. While these coupling reactions have been well utilized with simple haloarenes or halo‐olefins, now they are fast emerging on halotriazoles as well. This review summarizes the development of coupling reactions on halotriazoles, some of which are also biological relevant.