Dexmedetomidine inhibits apoptosis of astrocytes induced by oxygen-glucose deprivation via targeting JAK/STAT3 signal pathway

Randomized Assessment of Rapid Endovascular Treatment of Ischemic Stroke

Mayank Goyal, Andrew M. Demchuk, Bijoy K. Menon et al. · New England Journal of Medicine · 2015 · 6K citations · Full text

Medicine, Neurology, Cerebrovascular Neurosurgery +12

Tau exacerbates excitotoxic brain damage in an animal model of stroke

Mian Bi, Amadeus Gladbach, Janet van Eersel et al. · Nature Communications · 2017 · 171 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Dexmedetomidine inhibits astrocyte pyroptosis and subsequently protects the brain in in vitro and in vivo models of sepsis

Yibing Sun, Hailin Zhao, Dong-Liang Mu et al. · Cell Death and Disease · 2019 · 166 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Perioperative dexmedetomidine reduces the incidence and severity of acute kidney injury following valvular heart surgery

Jin Sun Cho, Jae‐Kwang Shim, Min Kyung Kim et al. · Kidney International · 2015 · 152 citations · Full text

Medicine, Perioperative Medicine, Surgery +13

Dexmedetomidine Protects Mouse Brain from Ischemia-Reperfusion Injury via Inhibiting Neuronal Autophagy through Up-Regulating HIF-1α

Cong Luo, Ming-Wen Ouyang, Yingying Fang et al. · Frontiers in Cellular Neuroscience · 2017 · 117 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17