Sevoflurane Suppresses Glioma Cell Proliferation, Migration, and Invasion Both <i>In Vitro</i> and <i>In Vivo</i> Partially Via Regulating KCNQ1OT1/miR-146b-5p/STC1 Axis

Jian Wen, Yan Ding, Shaohua Zheng, Xin Li, Ying Xiao

Cancer Biotherapy and Radiopharmaceuticals · 2020 · 10 citations · 30 references

Concepts

Abstract

Background: Sevoflurane (Sev), a volatile anesthetic agent, is widely used in neurosurgery for anesthesia maintenance, accompanied with antitumor activity postanesthesia in multiple human cancers, including glioma. However, the molecular mechanism of Sev in glioma is largely unclear, including associated informative noncoding RNAs, such as long noncoding RNAs (lncRNA) and microRNAs (miRNAs).

References

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