Concepedia

Hemoglobin-mediated biomimetic synthesis of paramagnetic O<sub>2</sub>-evolving theranostic nanoprobes for MR imaging-guided enhanced photodynamic therapy of tumor

Xiudong Shi, Weitao Yang, Qiong Ma, Yang Lü, Yan Xu, Kexin Bian, Fengjun Liu, Chunzi Shi, Han Wang, Yuxin Shi,

Theranostics · 2020 · 62 citations · 39 references

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Concepts

Abstract

In this study, by using a human endogenous protein, we demonstrated the biomimetic synthesis of multi-functional nanoprobes for simultaneous tumor oxygenation and imaging-guided enhanced PDT. The therapeutic efficacy could be quantitatively confirmed at 6 h post PDT with diffusion-weighted imaging (DWI).

References

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