Didymin ameliorates dexamethasone-induced non-alcoholic fatty liver disease by inhibiting TLR4/NF-κB and PI3K/Akt pathways in C57BL/6J mice

The Diagnosis and Management of Non-alcoholic Fatty Liver Disease: Practice Guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology

Naga Chalasani, Zobair M. Younossi, Joel E. Lavine et al. · Gastroenterology · 2012 · 1.8K citations · Full text

Medicine, Internal Medicine, Gastroenterology +15

Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

Vanessa S. Marsden, Liam O’Connor, Lorraine A. O’Reilly et al. · Nature · 2002 · 568 citations

Life Sciences, Cell Biology, Molecular Biology +14

Central role for liver X receptor in insulin-mediated activation of <i>Srebp-1c</i> transcription and stimulation of fatty acid synthesis in liver

Guoxun Chen, Guosheng Liang, Jiafu Ou et al. · Proceedings of the National Academy of Sciences · 2004 · 539 citations · Full text

Life Sciences, Endocrinology, Molecular Biology +16

Tumour necrosis factor α signalling through activation of Kupffer cells plays an essential role in liver fibrosis of non-alcoholic steatohepatitis in mice

Kengo Tomita, Gen Tamiya, Satoshi Ando et al. · Gut · 2005 · 430 citations · Full text

Life Sciences, Cell Biology, Pathobiology +17

Lack of interleukin-1α or interleukin-1β inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice

Yehuda Kamari, Aviv Shaish, Einav Vax et al. · Journal of Hepatology · 2011 · 285 citations · Full text

Life Sciences, Immunology, Pathology +12