Concepedia

Arrhythmic safety of hydroxychloroquine in COVID-19 patients from different clinical settings

Alessio Gasperetti, Mauro Biffi, Marco Schiavone, Matteo Ziacchi, Gianfranco Mitacchione, Carlo Lavalle, Ardan M. Saguner, Antonio Lanfranchi, Giacomo Casalini, Marco Tocci,

EP Europace · 2020 · 31 citations · 16 references

DOIFull text

Open access

Abstract

HCQ administration is safe for a short-term treatment for patients with COVID-19 infection regardless of the clinical setting of delivery, causing only modest QTc prolongation and no directly attributable arrhythmic deaths.

References

16

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges

Chih‐Cheng Lai, Tzu-Ping Shih, Wen‐Chien Ko et al. · International Journal of Antimicrobial Agents · 2020 · 6.3K citations · Full text

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A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19

Bin Cao, Yeming Wang, Danning Wen et al. · New England Journal of Medicine · 2020 · 5.5K citations · Full text

RETRACTED: Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial

Philippe Gautret, Jean‐Christophe Lagier, Philippe Parola et al. · International Journal of Antimicrobial Agents · 2020 · 4.9K citations · Full text

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Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies

Jianjun Gao, Zhenxue Tian, Xu Yang · BioScience Trends · 2020 · 2.7K citations · Full text

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Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19

Joshua D. Geleris, Yifei Sun, Jonathan Platt et al. · New England Journal of Medicine · 2020 · 1.7K citations · Full text