medRxiv · 2020 · 16 citations · 13 references
Veterinary MedicineClinical SciencesInfectious DiseasesEpidemiologyInfectious Disease EpidemiologyInfectious Disease Risk FactorsInfectious Disease SurveillanceDemographic CharacterizationDescriptive Case StudyInfectious Disease ManagementInfectious Disease Prevalence
ABSTRACT Introduction COVID-19 is an emerging, rapidly evolving global situation, infecting over 25 million people and causing more than 850,000 deaths. Several signs and symptoms have been described to be characteristic of the disease. However, there is a dearth of report on the description of the clinical characteristics of the disease in patients from Nigeria. This study was designed to provide a description of the clinical and demographic characteristics of COVID-19 patients in Nigeria. Methods This study is a case series that includes patients that are evaluated between June and August 30, 2020, and diagnosed with COVID-19. Patient health records were reviewed and evaluated to describe the clinical characteristics on presentation. Results A total of 154 COVID-19 patients were included in this study, with a mean age (S.D.) of 46.16 (13.701). Most of the patients survived (mortality rate of 2.6%), and were symptomatic (89.6%). There were more males (74.7%) than females, and the most common symptoms were fever, breathing difficulty, dry cough and malaise. Co-morbidities were also present in almost half of the study participants (49.4%). Conclusion This study presents the most extensive description, to date, on the clinical and demographic characteristics of COVID-19 patients in Nigeria. Males are more likely than females to be infected with COVID-19 and the most occurring symptoms are fever, breathing difficulty, malaise, dry cough and chest pain. Old age and the presence of co-morbidities may also be associated with developing the severe disease.
13
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang, Yeming Wang, Xingwang Li et al. · The Lancet · 2020 · 51.8K citations · Full text
Jasper Fuk‐Woo Chan, Shuofeng Yuan, Kin‐Hang Kok et al. · The Lancet · 2020 · 9.6K citations · Full text
Veterinary Medicine, Infectious Disease Control, Infectious Diseases +13
Why does COVID-19 disproportionately affect older people?
Amber L. Mueller, Maeve S. McNamara, David Sinclair · Aging · 2020 · 1.2K citations · Full text