Concepedia

Publication | Open Access

DCLK1, a Putative Stem Cell Marker in Human Cholangiocarcinoma

DOIFull Paper Access

43

Citations

36

References

2020

Year

Lorenzo Nevi, Sabina Di Matteo, Guido Carpino, Ilaria Grazia Zizzari, S. Safarikia, Valeria Ambrosino, D. Costantini, Diletta Overi, Marco Monti, Daniela Bosco,
Hepatology

Abstract

DCLK1 characterizes a specific CSC subpopulation of iCCA<sup>CD133+</sup> and pCCA<sup>LGR5+</sup> , and its inhibition exerts anti-neoplastic effects in primary CCA cell cultures. Human DCLK1 serum might represent a serum biomarker for the early CCA diagnosis.

References

YearCitations

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