Artificial Nanotargeted Cells with Stable Photothermal Performance for Multimodal Imaging-Guided Tumor-Specific Therapy

Bin Qiao, Yuanli Luo, Hong‐Bo Cheng, Jianli Ren, Jin Cao, Chao Yang, Bing Liang, Anyu Yang, Xun Yuan, Liming Deng,

ACS Nano · 2020 · 115 citations · 42 references

Concepts

Abstract

nanoparticles to achieve ANTC with TME-stable photothermal performance and tumor-specific phototherapy. The resulting ANTC can be used as contrast agents for concurrent photoacoustic imaging, magnetic resonance imaging, and photothermal imaging to guide the treatment. Importantly, the high loading efficiency of protoporphyrin enables the initiation of photodynamic therapy to enhance photothermal therapeutic efficiency, providing antitumor function with minimal side effects.

References

42