Concepedia

Publication | Open Access

<p>Targeted Inhibition of P4HB Promotes Cell Sensitivity to Gemcitabine in Urothelial Carcinoma of the Bladder</p>

DOIFull Paper Access

37

Citations

24

References

2020

Year

Xiaoming Wang, Yunjin Bai, Facai Zhang, Yubo Yang, Dechao Feng, Ao Li, Zhiqiang Yang, Dengxiong Li, Yin Tang, Xin Wei,
OncoTargets and Therapy

Abstract

High P4HB expression was significantly correlated with poor prognosis in BC patients. Inhibition of P4HB by BAC decreased the cell proliferation ability and sensitized BC cells to GEM by activating apoptosis and the PERK/eIF2α/ATF4/CHOP pathways.

References

YearCitations

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