NLRP12 negatively regulates EtOH-induced liver macrophage activation via NF-κB pathway and mediates hepatocyte apoptosis in alcoholic liver injury

Global burden of disease and injury and economic cost attributable to alcohol use and alcohol-use disorders

Jürgen Rehm, Colin Mathers, Svetlana Popova et al. · The Lancet · 2009 · 3.8K citations

Global Burden, Substance Abuse, Alcohol Misuse +14

Mouse model of chronic and binge ethanol feeding (the NIAAA model)

Adeline Bertola, Stephanie Mathews, Sung Hwan Ki et al. · Nature Protocols · 2013 · 1.2K citations · Full text

Energy Homeostasis, Binge Ethanol Feeding, Behavioral Neuroscience +14

Alcoholic Liver Disease: Pathogenesis and Current Management

Alcohol research · 2017 · 673 citations · Full text

Liver Fibrosis, Pathology, Excessive Alcohol Consumption +23

NLRP12 Suppresses Colon Inflammation and Tumorigenesis through the Negative Regulation of Noncanonical NF-κB Signaling

Irving C. Allen, Justin E. Wilson, Monika Schneider et al. · Immunity · 2012 · 544 citations · Full text

Inflammation, Mucosal Immunology, Noncanonical Nf-κb Signaling +10

Protective Effects of Taraxasterol against Ethanol‐Induced Liver Injury by Regulating CYP2E1/Nrf2/HO‐1 and NF‐<i>κ</i>B Signaling Pathways in Mice

Lu Xu, Yifan Yu, Rui Sang et al. · Oxidative Medicine and Cellular Longevity · 2018 · 309 citations · Full text