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Mitoxantrone impairs proteasome activity and prompts early energetic and proteomic changes in HL-1 cardiomyocytes at clinically relevant concentrations

Proteomic ChangesMitophagyCardiomyopathyMolecular PhysiologyHl-1 CardiomyocytesMedicinePhysiologyMetabolic RemodelingMetabolomicsCardiovascular ToxicityPharmacologyCell BiologyProteasome ActivityOxidative Stress